Publications

Validation requirements for AI-based intervention-evaluation in aging and longevity research and practice

G Fuellen, A Kulaga, S Lobentanzer, M Unfried, RA Avelar, D Palmer, et al.

Ageing Research Reviews·2025·17 citations

Conserved biological processes in partial cellular reprogramming: Relevance to aging and rejuvenation

RA Avelar, D Palmer, AY Kulaga, G Fuellen

Ageing Research Reviews·2025·9 citations

In-silico evaluation of aging-related interventions using omics data and predictive modeling

G Fuellen, D Palmer, C Fruijtier, RA Avelar

Ageing Research Reviews·2025·3 citations

Animal and vegetal materials of mouse oocytes segregate at first zygotic cleavage: a simple mechanism that makes the two-cell blastomeres differ reciprocally from the start

T Nolte, R Halabian, S Israel, Y Suzuki, RA Avelar, D Palmer, G Fuellen, et al.

Molecular human reproduction·2025·3 citations

Insights into the in vitro ichthyotoxicity on fish gill cells and toxin production of Karlodinium veneficum (Dinophyceae) strains from French waters

R Beesoo, K Hogeveen, F Hervé, D Réveillon, C Boucher, et al.

Harmful Algae·2025·2 citations

Human Ageing Genomic Resources: updates on key databases in ageing research

JP de Magalhães, Z Abidi, GA Dos Santos, RA Avelar, D Barardo, et al.

Nucleic acids research·2024·174 citations

Mosaic regulation of stress pathways underlies senescent cell heterogeneity

RA Avelar, T Duffield, C Lagger, N Krstevska, M Breuer, JP de Magalhães

bioRxiv·2024preprint·5 citations

Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis

TD Admasu, K Kim, M Rae, R Avelar, RL Gonciarz, A Rebbaa, et al.

Cell Reports·2023·65 citations

scDiffCom: a tool for differential analysis of cell–cell interactions provides a mouse atlas of aging changes in intercellular communication

C Lagger, E Ursu, A Equey, RA Avelar, AO Pisco, R Tacutu, et al.

Nature Aging·2023·37 citations

Transcriptomic analysis reveals a tissue-specific loss of identity during ageing and cancer

GA Dos Santos, K Chatsirisupachai, RA Avelar, JP de Magalhães

BMC genomics·2023·28 citations

Positive selection and enhancer evolution shaped lifespan and body mass in great apes

D Tejada-Martinez, RA Avelar, I Lopes, B Zhang, G Novoa, et al.

Molecular Biology and Evolution·2022·34 citations

Identifying novel osteoarthritis-associated genes in human cartilage using a systematic meta-analysis and a multi-source integrated network

E Shorter, R Avelar, M Zachariou, GM Spyrou, P Raina, A Smagul, et al.

International Journal of Molecular Sciences·2022·22 citations

Potential senotherapeutic candidates and their combinations derived from transcriptional connectivity and network measures

AN Rad, G Shams, RA Avelar, MH Morowvat, Y Ghasemi

Informatics in Medicine Unlocked·2022·8 citations

A multidimensional systems biology analysis of cellular senescence in aging and disease

RA Avelar, JG Ortega, R Tacutu, EJ Tyler, D Bennett, P Binetti, et al.

Genome biology·2020·466 citations