avelar.science

Roberto Avelar

Chief Scientific Officer at Sustayn Bioscience. Aging & longevity research, bioinformatics, and AI.

About

I'm from Colombia and have lived in 10 different countries. I did my undergraduate and master's degrees at the University of York (2013–2017), and my PhD (2018–2022) in João Pedro de Magalhães' lab at the University of Liverpool.

My first postdoc was at the CRUK Cambridge Institute in Masashi Narita's lab, working with Wolf Reik, followed by a second postdoc at the University of Rostock with Georg Fuellen.

I'm now Chief Scientific Officer at Sustayn Bioscience, helping anti-aging and chronic disease companies predict novel, safe compounds using knowledge graphs, bioinformatics, and AI methods.

Publications

full list on Google Scholar ↗

sourced from Google Scholar · updated 2026-06-11

  1. Validation requirements for AI-based intervention-evaluation in aging and longevity research and practice

    G Fuellen, A Kulaga, S Lobentanzer, M Unfried, RA Avelar, D Palmer, et al.

    Ageing Research Reviews·2025·11 citations

  2. Conserved biological processes in partial cellular reprogramming: Relevance to aging and rejuvenation

    RA Avelar, D Palmer, AY Kulaga, G Fuellen

    Ageing Research Reviews·2025·5 citations

  3. Animal and vegetal materials of mouse oocytes segregate at first zygotic cleavage: a simple mechanism that makes the two-cell blastomeres differ reciprocally from the start

    T Nolte, R Halabian, S Israel, Y Suzuki, RA Avelar, D Palmer, G Fuellen, et al.

    Molecular human reproduction·2025·2 citations

  4. Insights into the in vitro ichthyotoxicity on fish gill cells and toxin production of Karlodinium veneficum (Dinophyceae) strains from French waters

    R Beesoo, K Hogeveen, F Hervé, D Réveillon, C Boucher, et al.

    Harmful Algae·2025·1 citation

  5. In-silico evaluation of aging-related interventions using omics data and predictive modeling

    G Fuellen, D Palmer, C Fruijtier, RA Avelar

    Ageing Research Reviews·2025·1 citation

  6. Human Ageing Genomic Resources: updates on key databases in ageing research

    JP de Magalhães, Z Abidi, GA Dos Santos, RA Avelar, D Barardo, et al.

    Nucleic Acids Research·2024·133 citations

  7. Mosaic regulation of stress pathways underlies senescent cell heterogeneity

    RA Avelar, T Duffield, C Lagger, N Krstevska, M Breuer, JP de Magalhães

    bioRxiv·2024preprint·3 citations

  8. Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis

    TD Admasu, K Kim, M Rae, R Avelar, RL Gonciarz, A Rebbaa, et al.

    Cell Reports·2023·56 citations

  9. scDiffCom: a tool for differential analysis of cell–cell interactions provides a mouse atlas of aging changes in intercellular communication

    C Lagger, E Ursu, A Equey, RA Avelar, AO Pisco, R Tacutu, et al.

    Nature Aging·2023·27 citations

  10. Transcriptomic analysis reveals a tissue-specific loss of identity during ageing and cancer

    GA Dos Santos, K Chatsirisupachai, RA Avelar, JP de Magalhães

    BMC genomics·2023·20 citations

  11. Positive selection and enhancer evolution shaped lifespan and body mass in great apes

    D Tejada-Martinez, RA Avelar, I Lopes, B Zhang, G Novoa, et al.

    Molecular Biology and Evolution·2022·29 citations

  12. Identifying novel osteoarthritis-associated genes in human cartilage using a systematic meta-analysis and a multi-source integrated network

    E Shorter, R Avelar, M Zachariou, GM Spyrou, P Raina, A Smagul, et al.

    International Journal of Molecular Sciences·2022·23 citations

  13. Potential senotherapeutic candidates and their combinations derived from transcriptional connectivity and network measures

    AN Rad, G Shams, RA Avelar, MH Morowvat, Y Ghasemi

    Informatics in Medicine Unlocked·2022·8 citations

  14. A multidimensional systems biology analysis of cellular senescence in aging and disease

    RA Avelar, JG Ortega, R Tacutu, EJ Tyler, D Bennett, P Binetti, et al.

    Genome biology·2020·421 citations